Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GJA1 (Cx43) - context-dependent: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| cell biology | promoted: Context-Dependent Cx43 Modulation Based on Disease Stage | disease | 0.58 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Context-Dependent Cx43 Modulation Based on Disease Stage | 0.579 | cell biology | What is the relative contribution of con |
Scientific analyses that reference this entity
cell biology | 2026-04-12 | 2 hypotheses Top: 0.579
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine [PMID:40946315] | Mulkearns-Hubert EE, Hajdari N, Hong ES, | Cell Rep | 2025 | 0 |
| Integrative analysis of gene expression and histone modifications for DES, DSP, [PMID:41275133] | Saeed S, Hoffmann A, Svensson SIA, Visno | Mol Med | 2025 | 0 |